As covid-19 surges in Mississippi, some people are ingesting an unproven livestock dewormer
Mississippi State Epidemiologist Paul Byers warned that “at least 70 percent of the recent calls” to poison control have been related to the ingestion of ivermectin “purchased at livestock supply centers.”washingtonpost.com
Pfizer begins early stage clinical trial testing oral antiviral drug for Covid
Pfizer said Tuesday it has begun an early stage clinical trial of an experimental oral antiviral drug for Covid-19. The New York-based company said the phase one trial of the drug – called PF-07321332 – is being conducted in the United States. The drug is part of a class of medicines called protease inhibitors and works by inhibiting an enzyme that the virus needs to replicate in human cells. The trial comes as Pfizer is also working on an intravenously administered protease inhibitor, known as PF-07304814. That drug is currently in a phase 1b clinical trial in patients hospitalized with Covid-19.cnbc.com
Details on experimental drug being used to treat HFD captain battling COVID-19
WOODLANDS, Texas – A Houston firefighter's family is hoping a new drug will help him win his battle with COVID-19. According to the U.S. National Library of Medicine, there are four hospitals across the country experimenting with the drug. Now, the company that makes the drug, NeuroRX, says they believe by using it as an injection, it can be used for conditions like bipolar depression and also respiratory distress. The department said they got approval from NeuroRX to get the drug transferred from Houston Methodist to Memorial Hermann in the Woodlands to treat Capt. Pena added that, right now, 96 Houston firefighters are in quarantine and 34 firefighters have tested positive.
FDA has fast-tracked promising drug to treat COVID-19 patients and it is in trial at Houston Methodist
HOUSTON – The U.S. Food and Drug Administration has fast-tracked a promising drug to treat COVID-19 patients and it is in trial at Houston Methodist Hospital. The drug is called RLF-100 and is also known as aviptadil. It has been approved by the FDA for emergency use at multiple clinical sites in patients who are too ill to enter the FDA’s Phase 2/3 trials. According to a press release from the drug maker NeuroRX, independent researchers have reported that aviptadil blocked replication of the SARS coronavirus in human lung cells and monocytes. The drug has been successful in reducing lung inflammation and so the FDA now says any doctor at any hospital can request this treatment to help severely ill COVID-19 patients.
US stuck with stockpile of 63M doses of hydroxychloroquine after FDA revokes emergency use authorization
(CNN) – The federal government is stuck with 63 million doses of hydroxychloroquine now that the US Food and Drug Administration has revoked permission for the drug to be distributed to treat coronavirus patients. The government started stockpiling donated hydroxychloroquine in late March, after President Trump touted it as "very encouraging" and "very powerful" and a "game-changer." That leaves the Strategic National Stockpile with 63 million doses of hydroxychloroquine, plus another 2 million doses of chloroquine, a related drug donated by Bayer, according to Carol Danko, a spokesperson for the US Department of Health and Human Services. Before the FDA revoked its authorization, the stockpile had already distributed 31 million doses. Novartis and Mylan donated doses of the drug to the stockpile.
New drug offering new hope for women with osteoporosis
Nearly 10 million Americans suffer from osteoporosis, and now a new drug may be about to change the way it's treated. It doesn't have a formal name yet but when injected daily, it reduces fractures and increases bone density in patients. The drug appears to reverse the affects of osteoporosis by stimulating cells to create new bone. "The ability to improve bone quality is a new concept and that's what this agent does," Dr. Paul Miller with Centura Health Physician Group says. Read more at KUSA
LSD-type narcotic 25i sending users to emergency rooms
LSD-type narcotic 25i sending users to emergency rooms Police say a new drug, with nicknames like 25i, N-Bomb and Smiles, is a dangerous narcotic that first gives the user a euphoric feeling, but then can cause disorientation and violent behavior. In the most dangerous cases, the drug causes a rapid heart rate which has led to deaths. WUSA's Peggy Fox reports.cbsnews.com