Police were unable to disclose if the two people who died were from either the motorcycle or car involved in the crash.

Here is what you need to know about 610 closures this weekend:

A hazmat spill temporarily closed several eastbound lanes on the IH-610 South Loop following a multi-vehicle crash on Thursday afternoon, according to Houston Transtar.

A crash involving an 18-wheeler has shut down the 610 South Loop eastbound after Crestmont Wednesday, the Houston Police Department said.

A Houston Police Department officer has been transported to the hospital after crashing into a wall on 610 South Loop at Stella Link on Friday.

All westbound mainlanes at 610 South Loop are closed after a 5-vehicle crash near Crestmont Street, according to Houston TranStar.

The 610 South Loop eastbound at Telephone Road is completely shut down Wednesday.

All mainlanes at 610 South Loop are shut down near Highway 288 due to downed power lines, according to TxDOT.

Three lanes on the 610 South Loop at Cullen Blvd are shut down due to a major crash involving two vehicles and a pedestrian.

A man was struck by a car and killed while crossing 610 South Loop Sunday night, according to Houston police. The accident happened around 9:14 p.m. Sunday on 610 South Loop near Highway 288, near Almeda. Houston police said the man walked across the eastbound lanes of 610 South Loop was hit and killed. Several lanes in the area are blocked.

2 mainlanes of Gulf Freeway inbound are closed at 610 South LoopPublished: October 10, 2013, 8:36 amTwo mainlanes of the Gulf Freeway North are closed at the 610 South Loop for a three-vehicle accident. Click here for traffic updates. Copyright 2013 by Click2Houston.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.