ATLANTA (CNN) - Another blast of severe weather will kick off Wednesday in the central and southern United States, even as some of those places are still recovering from last week's deadly storm system.
The storms will barrel toward the East Coast through Friday, unleashing tornadoes, damaging winds and hail along the way, from the Texas Panhandle to the coast of the Carolinas.
Over three days, the storm will affect more than 100 million people and traverse about 1,400 miles, including parts of the Southeast and Mid-Atlantic that got battered over the weekend by severe weather.
As the system treks east, parts of the Southeast could experience severe weather on Thursday, with a large swath of the East Coast on track to feel impacts on Friday.
"The greatest threat will be damaging winds and very large hail, but tornadoes will also be possible," the National Weather Service said.
A massive storm system killed eight people in the South over the weekend and caused damage from Texas to Mississippi. Four people died in Texas, two in Louisiana, one in Mississippi and another in Alabama.
Wednesday: From Texas to Kansas
Severe thunderstorm watches are in effect from Texas to Missouri through Wednesday night, with some extending into early Thursday morning, said CNN meteorologist Michael Guy.
Hail is expected overnight in Texas and southern Oklahoma that could be 2 inches in diameter or greater as the cold front pushes through, he said. There were reports of minor tornadoes on Wednesday from Kansas down to north Texas but no reports of damage, Guy said.
Southwest Airlines and American Airlines canceled about 200 flights that had been scheduled for Wednesday evening at the Dallas-Forth Worh International and Dallas Love Field airports.
A spokesperson with American Airlines said the company planned to only keep a limited number of aircraft in Dallas overnight and "will look to use as much hangar space as possible to protect" its fleet.
All Louisiana state offices will be closed on Thursday, according to Gov. John Bel Edwards.
Thursday: From Louisiana to Tennessee
The threat of tornadoes will increase on Thursday as the storm system pushes east to Louisiana, Mississippi and Alabama, Guy said.
Louisiana and Mississippi will be at risk Thursday morning, with the storms moving into Alabama on Thursday evening through the overnight hours. The Deep South also faces an "enhanced risk" (Level 3 of 5) of severe storms, the Storm Prediction Center said.
Some cities facing that level of risk include Baton Rouge and New Orleans, Louisiana, and Mobile and Birmingham, Alabama. A "slight risk" (Level 2 of 5) has been declared in Memphis and Nashville, Tennessee.
Damaging winds and hail will continue to be a concern during this second day of severe weather.
Friday: From Florida to Washington
By early Friday morning, the system will move through Georgia and near the coastal Atlantic states by afternoon. The severe storm threat ramps up through the day from the southern tip of Florida to Washington, DC.
The coastal Carolinas and southeastern Virginia have the greatest potential for severe weather. That zone has been declared at "enhanced risk" (Level 3 of 5) by the Storm Prediction Center.
Overall conditions within the broad system should allow for a few individual storms to intensify. Damaging winds and tornadoes will be possible, especially within the "enhanced risk" area.
The threat should diminish throughout the overnight hours as the cold front associated with the potent storms finally pushes offshore.
CNN meteorologist Dave Hennen, Marlena Baldacci and Nicole Chavez contributed to this report.
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