HUMBLE -

Arson is investigating the cause of a massive fire that destroyed a home in Humble early Tuesday morning.

The fire broke out around 5:45 a.m. Tuesday in the 7600 block of Serene near Lee Road.

Officials had Lee Road completely shut down while firefighters worked to tap out the fire.

Firefighters with Northeast Fire Department, Aldine Fire Department, Eastex Fire Department, Houston Fire Department extinguished the flames.

Officials the homeowner had already moved out, so there was no one inside the home at the time of the blaze.

According to a neighbor, the owner, who is confined to a wheelchair, is ill and was staying with his mother at the time of the fire.

The fire marshal's office has been called out to investigate what caused the fire to start.