The Labor Day Weekend means it's a No Refusal weekend.
Officers will be on the lookout for impaired drivers.
Under the no refusal law, a search warrant will be issued to draw the blood of any suspected intoxicated driver who refuses to take a breathalyzer test or to give a blood sample.
Friday, Harris County officials held a news conference to announce the start of the initiative.
They were joined by the Patel family, who lost four loved ones to a drunk driving crash.
Harris County continues to top the list of counties nationwide with the most DWI-related fatalities.
The No Refusal initiative starts tonight and will continue through Monday morning.