A driver's turn into oncoming traffic caused a major head-on collision in the Crosby area.
It happened around 2:30 a.m. near the Beaumont Highway and Gulf Pump Road.
Authorities say a woman driving a Chevrolet Camaro drove the wrong way and turned into eastbound lanes of the highway, crashing into a Jeep.
The driver of the Camaro and two other women in the vehicle were transported to a hospital in serious but stable condition, according to officials.
Authorities say the driver in the Jeep was not seriously injured.