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Epilepsy Surgery May Not Be Last Resort

Study Looks At Treating Disease

UPDATED: 4:46 p.m. EDT October 6, 2003

According to the Epilepsy Foundation of America, 2.3 million people in the United States have epilepsy. Often diagnosed at a young age, many patients can go years -- even a lifetime -- with inadequate control of their seizures. Now, more aggressive treatment is getting patients back into life.

Margaret Weems, 29, was diagnosed with epilepsy at age 12.

"I pretty much could not ever be left alone," she said.

Even on medication, Weems had up to five seizures a week.

Dr. Jerome Engel Jr., a neurologist at the University of California-Los Angeles, said 30 percent of epileptic patients are not controlled with medication.

"There is no specific approach to the medical treatment, and it's trial and error by most physicians," he said.

When drugs fail, surgery is often used as a last resort -- partly because of the fear of brain surgery.

Engel is leading a study to find out if surgery earlier in the disease is a better option: "Epilepsy itself is much more dangerous than surgery. The risk of death from seizures is much greater than it is from surgery."

Surgery may be the best bet for many patients. Studies show one-third of patients remain seizure-free two years after surgery.

Weems had the surgery at 16. She hasn't had a seizure since.

"It's been awesome. It's been amazing," she said.

It took about a year to recover from not having seizures, but it was worth it.

"To go through one year of hard work of recuperating vs. the rest of your life of being frustrated, that's just a slam dunk," Weems said.

Engel said it often takes years for patients to go through the many different medications for epilepsy before it's determined that none of them will control their disease. By then, surgery is still an option, but the damage from the seizures is already done.

The trial to determine whether surgery or medication is best in the early stages of the disease is taking place at 19 sites nationwide.

If you would like more information, please contact:
    National Institutes of Health
    (800) 352-9424

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