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January 7, 2009

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'Baby' Fat Cells Wait For Extra Calories

Future Fat Hides In Walls Of Blood Vessels

POSTED: Friday, September 19, 2008

Researchers said they have discovered where immature fat cells hide in the body, lurking and waiting for extra calories that can turn them into "adult" cells that can add extra pounds.

A team from the University of Texas Southwestern Medical Center said they studied mice to learn the "baby" fat cells hide in the walls of blood vessels that supply fatty tissue.

They said in a news release the finding may lead to future research to find ways to stop these cells from creating undesired fat.

The baby cells could also be used for procedures such as filling in a woman's breast after a lumpectomy or helping heal scars.

"Because we have found their location, we might be able to develop therapies that can help people with obesity, diabetes or other metabolic challenges," said senior author Dr. Jonathan Graff.

The cells are normal, and usually replace dying fat cells. But when the active, adult cells grow too full, the baby cells, also known as progenitor cells, kick into action.

The study appears in the journal Science.
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